Sharmila Shankar Selected Research

Death Domain Receptors

10/2007	Curcumin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells: molecular mechanisms of apoptosis, migration and angiogenesis.
12/2005	Interactive effects of histone deacetylase inhibitors and TRAIL on apoptosis in human leukemia cells: involvement of both death receptor and mitochondrial pathways.
7/2005	HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma.
9/2004	Ionizing radiation enhances the therapeutic potential of TRAIL in prostate cancer in vitro and in vivo: Intracellular mechanisms.
4/2004	Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: mechanisms and clinical implications.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Sharmila Shankar Research Topics

Disease

44	Neoplasms (Cancer) 10/2020 - 09/2003
26	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 09/2007
16	Neoplasm Metastasis (Metastasis) 01/2020 - 09/2007
14	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 09/2004
9	Carcinogenesis 11/2021 - 01/2011
8	Breast Neoplasms (Breast Cancer) 01/2017 - 09/2003
2	Colorectal Neoplasms (Colorectal Cancer) 10/2020 - 01/2017
2	Inflammation (Inflammations) 01/2014 - 09/2007
2	Rheumatoid Arthritis 04/2010 - 03/2008
2	Psoriasis (Pustulosis Palmaris et Plantaris) 04/2010 - 03/2008
2	Diabetic Retinopathy (Retinopathy, Diabetic) 04/2010 - 03/2008
2	Hypoxia (Hypoxemia) 06/2009 - 08/2008
2	Cardiovascular Diseases (Cardiovascular Disease) 03/2008 - 09/2007
2	Mitochondrial Diseases (Mitochondrial Disease) 10/2007 - 02/2006
2	Multiple Myeloma 02/2006 - 07/2005
1	Stroke (Strokes) 11/2021
1	Insulin Resistance 11/2021
1	Type 2 Diabetes Mellitus (MODY) 11/2021
1	Myocardial Infarction 11/2021
1	Blindness (Hysterical Blindness) 11/2021
1	Renal Insufficiency (Renal Failure) 11/2021
1	Alzheimer Disease (Alzheimer's Disease) 01/2019
1	Amnesia (Dissociative Amnesia) 01/2019
1	Nervous System Diseases (Neurological Disorders) 08/2015
1	Peripheral Nervous System Diseases (PNS Diseases) 08/2015

Drug/Important Bio-Agent (IBA)

12	Transcription Factors (Transcription Factor)IBA 01/2016 - 03/2008
12	Caspase 3 (Caspase-3)IBA 01/2014 - 09/2003
11	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2014 - 09/2007
10	Cyclin D1IBA 01/2016 - 12/2007
9	ResveratrolIBA 01/2019 - 08/2007
9	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2010 - 09/2003
7	sulforaphaneIBA 01/2020 - 11/2008
7	Histone Deacetylase InhibitorsIBA 01/2011 - 07/2005
7	LigandsIBA 12/2010 - 09/2003
6	Proteins (Proteins, Gene)FDA Link 10/2020 - 08/2010
6	CaspasesIBA 12/2011 - 09/2004
6	CurcuminIBA 01/2008 - 04/2007
5	Death Domain ReceptorsIBA 10/2007 - 04/2004
4	Biomarkers (Surrogate Marker)IBA 10/2020 - 04/2013
4	Pharmaceutical PreparationsIBA 01/2019 - 08/2010
4	rottlerinIBA 10/2014 - 11/2012
4	Proliferating Cell Nuclear Antigen (PCNA)IBA 01/2014 - 01/2008
4	TeaIBA 01/2013 - 09/2007
4	Vorinostat FDA Link 01/2011 - 07/2005
4	NF-kappa B (NF-kB)IBA 06/2009 - 09/2007
4	TNF-Related Apoptosis-Inducing LigandIBA 10/2007 - 09/2003
3	mangostinIBA 10/2020 - 01/2016
3	Interleukin-6 (Interleukin 6)IBA 01/2014 - 08/2008
3	PolyphenolsIBA 01/2011 - 09/2007
3	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 12/2010 - 01/2008
3	entinostat (MS 275)IBA 12/2010 - 07/2005
3	Matrix Metalloproteinases (MMPs)IBA 12/2010 - 09/2007
3	AndrogensIBA 12/2007 - 04/2007
3	Cytochromes c (Cytochrome c)IBA 10/2007 - 12/2005
2	Ethanol (Ethyl Alcohol)IBA 01/2022 - 11/2021
2	CateninsIBA 01/2022 - 01/2017
2	Small Interfering RNA (siRNA)IBA 01/2017 - 05/2004
2	Cadherins (E-Cadherin)IBA 01/2016 - 01/2013
2	Biological ProductsIBA 01/2016 - 02/2006
2	Interleukin-8 (Interleukin 8)IBA 01/2014 - 06/2009
2	embelinIBA 01/2014 - 01/2014
2	Forkhead Transcription Factors (Forkhead Box Proteins)IBA 01/2013 - 01/2011
2	Antineoplastic Agents (Antineoplastics)IBA 12/2011 - 02/2005
2	Cell Cycle ProteinsIBA 12/2011 - 09/2007
2	VimentinIBA 01/2011 - 08/2010
2	beta CateninIBA 01/2011 - 08/2010
2	FlavonoidsIBA 01/2011 - 08/2010
2	QuercetinIBA 01/2011 - 08/2010
2	Histone Deacetylases (Histone Deacetylase)IBA 12/2010 - 12/2005
2	von Willebrand FactorIBA 12/2010 - 06/2009
2	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2008 - 02/2005
2	Etoposide (VP 16)FDA LinkGeneric 06/2008 - 02/2005
2	Paclitaxel (Taxol)FDA LinkGeneric 06/2008 - 02/2005
2	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 01/2008 - 09/2007
2	Mitochondrial Proteins (Mitochondrial Protein)IBA 10/2007 - 12/2005
2	trichostatin A (A 300)IBA 12/2005 - 07/2005
2	theasinensin AIBA 12/2005 - 07/2005
1	Riluzole FDA LinkGeneric 01/2022
1	Glutamine (L-Glutamine)FDA Link 01/2022
1	Glucose (Dextrose)FDA LinkGeneric 01/2022
1	Blood Glucose (Blood Sugar)IBA 11/2021
1	Notch ReceptorsIBA 10/2020
1	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2019
1	4-Aminobenzoic Acid (4 Aminobenzoic Acid)IBA 01/2019
1	Donepezil (Aricept)FDA LinkGeneric 01/2019
1	sanguinarineIBA 10/2017
1	Antimalarials (Antimalarial Agents)IBA 11/2015
1	anthothecolIBA 11/2015
1	MicroRNAs (MicroRNA)IBA 10/2015
1	TetraspaninsIBA 02/2015
1	RotenoneIBA 02/2015
1	Ellagic AcidIBA 09/2013
1	PhytochemicalsIBA 04/2013
1	GANT 61IBA 03/2013
1	NeuropilinsIBA 01/2013
1	tofacitinibIBA 01/2012
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2012

Therapy/Procedure

16	Therapeutics 08/2015 - 09/2003
4	Drug Therapy (Chemotherapy) 08/2015 - 04/2004
1	Surgical Amputation (Amputations) 11/2021